Assistant professor Uijeongbu Eulji Medical Center, United States
Research Objectives: This study investigated bone mineral density test and prevalence of low bone mass in young adults with spinal cord injury(SCI).
Design: Prospective cross sectional study .
Setting: Inpatients at the National Rehabilitation Center.
Participants: Patients with SCI aged 20-49 years hospitalized from January 2010 to October 2021
Interventions: Bone mineral density was assessed using dual-energy X-ray absorptiometry
Main Outcome Measures: Bone mineral density and T-score of the lumbar spine, femoral neck, and total hip.
Results: Osteopenia was diagnosed in 451 patients (58.2%), and osteoporosis was diagnosed in 156 (20.1%) of 775 patients. Among 181 patients with time from injury within 3 months, 105 (58%) and 20 (11%) were diagnosed with osteopenia and osteoporosis, respectively. Additionally, the percentage of LBM increased significantly as the time from injury increased. On multivariate analysis, the risk factors for LBM in patients with acute SCI within 12 months of onset were age (odds ratio [OR]=1.04; 95% confidence interval (CI), 1.01 to 1.07; p=0.005), female sex (OR=2.49; 95% CI, 1.34 to 4.46; p=0.002), and body mass index (OR=0.86; 95% CI, 0.81 to 0.92; p< 0.001). Furthermore, alcohol or smoking history, etiology of injury, neurological level of injury, completeness of injury, and the Korean version of the spinal cord independence measure-III score were not significantly correlated with LBM.
Conclusions: The prevalence of osteopenia and osteoporosis is high in young adults with SCI. In addition, the diagnosis rate is high in the test performed at the initial stages after injury. Therefore, early bone health monitoring should be performed in young adults with SCI.
Author(s) Disclosures: All authors declare there are not any conflicts
Learning Objectives:
Upon completion, participants will be able to know the incidence of osteoporosis is higher in young SCI patients than in non-disabled people.
Upon completion, paricipant will be able to know the necessity of early BMD testing after SCI.
Upon completion, paricipant will be able to know that SCI patients have the similar risk factors for development of osteoporosis as the general population.
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